A cloud-based clinical genomics platform for precision medicine
PLATFORMS
Supports all major NGS platforms and can easily adopt new sequencing technologies.
FILE FORMATS
Supports FastQ and VCF file formats.
ANALYSIS WORKFLOW
Customized high throughput NGS analysis workflows for individuals, case-control and family samples, and cohort studies.
GENE PANELS
A single comprehensive platform that supports all industry standard oncology and hereditary panels as well as custom panels.
VARIANT PRIORITIZATION
Powerful and flexible Variant Interpretation & Prioritization (ViP) engine provides clinical grade variants.
CLINICAL REPORTING
Decision support with high impact pathogenic variants, pharmacogenomics evidence, and therapeutic information including FDA approved drugs, and associated side effects.
GUIDELINES
Variant prioritization and interpretation based on ACMG, NCCN, ASCO and ESMO clinical guidelines.
PATHOGEN IDENTIFICATION
Support for ampliseq panels, exomes and whole genomes.
PLATFORMS
Supports all major NGS platforms and can easily adopt new sequencing technologies.
FILE FORMATS
Supports FastQ and VCF file formats.
ANALYSIS WORKFLOW
Customized high throughput NGS analysis workflows for individuals, case-control and family samples, and cohort studies.
GENE PANELS
A single comprehensive platform that supports all industry standard oncology and hereditary panels as well as custom panels.
VARIANT PRIORITIZATION
Powerful and flexible Variant Interpretation & Prioritization (ViP) engine provides clinical grade variants.
CLINICAL REPORTING
Decision support with high impact pathogenic variants, pharmacogenomics evidence, and therapeutic information including FDA approved drugs, and associated side effects.
GUIDELINES
Variant prioritization and interpretation based on ACMG, NCCN, ASCO and ESMO clinical guidelines.
PATHOGEN IDENTIFICATION
Support for ampliseq panels, exomes and whole genomes.
Transforming genomic intelligence into targeted therapies
Oncology
For various cancers, the platform supports both commercial panels from Illumina, Ion AmpliSeq, and user-specific custom panels. A wide range of comprehensive and tailored Somatic, Germline and Gene Fusion panels consist of highly curated and validated genes associated with targeted treatments, either FDA-approved or active clinical trials.
Inherited Disorders
Identify specific genetic causes of inherited and metabolic disorders. The platform supports leading industry panels, providing a quick, accurate, and cost-effective method to identify genetic mutations associated with inherited disorders.
GEx KnowledgeBase
GEx knowledgebase acts as an intelligent system to decode the complexities of genomic data.
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Biological Information
hg19, dbSNP, OMIM
Biological Informationhg19, dbSNP, OMIM
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Cancer Databases
COSMIC, ClinVar
Cancer DatabasesCOSMIC, ClinVar
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Population Frequency Databases
1000 Genomes, Exome Sequencing project (ESP), Exome Aggregation Consortium (ExAC)
Population Frequency Databases1000 Genomes, Exome Sequencing project (ESP), Exome Aggregation Consortium (ExAC)
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Curated Publications
Curated and categorized PubMed evidences for 1,256 diseases, 1,181 gene panels, 7,715 clinically relevant genes, 44,558 curated top-tier disease-driving variants, 291 targeted therapies, 109 drug label annotations and 23 actionable pathways.
Curated PublicationsCurated and categorized PubMed evidences for 1,256 diseases, 1,181 gene panels, 7,715 clinically relevant genes, 44,558 curated top-tier disease-driving variants, 291 targeted therapies, 109 drug label annotations and 23 actionable pathways.
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case-control, family analysis (Trio) & cohort analysis
Security and Compliance
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Data at Rest and in Transit
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Data Privacy / Security*
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Application Security
As a comprehensive solution, Genome Explorer® is offered on Amazon Web Services (AWS) Cloud platform.
Genome Explorer® application development, cloud deployment, app usage, data transition and processing, and user access are compliant with standard data security and privacy measures.
Genome Explorer® adheres to the AWS Compliance Program.
Data at Rest and in Transit
As a comprehensive solution, Genome Explorer® is offered on Amazon Web Services (AWS) Cloud platform.
Data Privacy / Security*
Genome Explorer® application development, cloud deployment, app usage, data transition and processing, and user access are compliant with standard data security and privacy measures.
Application Security
Genome Explorer® adheres to the AWS Compliance Program.